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Dovitinib Dilactic Acid

CAS No. 852433-84-2

Dovitinib Dilactic Acid ( Dovitinib Dilactic acid; TKI258 Dilactic acid; CHIR-258, TKI258 )

产品货号. M17618 CAS No. 852433-84-2

Dovitinib Dilactic acid (TKI258 Dilactic acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor.

纯度: 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥608 有现货
10MG ¥923 有现货
25MG ¥1895 有现货
50MG ¥3281 有现货
100MG ¥5249 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Dovitinib Dilactic Acid
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Dovitinib Dilactic acid (TKI258 Dilactic acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor.
  • 产品描述
    Dovitinib Dilactic acid (TKI258 Dilactic acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4.
  • 同义词
    Dovitinib Dilactic acid; TKI258 Dilactic acid; CHIR-258, TKI258
  • 通路
    Metabolic Enzyme/Protease
  • 靶点
    Dehydrogenase
  • 受体
    c-Kit; FGFR1; FGFR3; FLT3; VEGFR3/FLT4
  • 研究领域
    Cancer
  • 适应症
    ——

化学信息

  • CAS Number
    852433-84-2
  • 分子量
    572.59
  • 分子式
    C21H21FN6O·2C3H6O3
  • 纯度
    98%
  • 溶解度
    ——
  • SMILES
    CC(C(=O)O)O.CC(C(=O)O)O.CN1CCN(CC1)C2=CC3=C(C=C2)N/C(=C/4\C(=C5C(=NC4=O)C=CC=C5F)N)/N3
  • 化学全称
    2-Hydroxypropanoic acid compd. with 4-amino-5-fluoro-3-[6-(4-methyl-1- piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Trudel S, et al. Blood. 2005, 105(7), 2941-2948.
产品手册
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