Dovitinib Dilactic Acid
CAS No. 852433-84-2
Dovitinib Dilactic Acid ( Dovitinib Dilactic acid; TKI258 Dilactic acid; CHIR-258, TKI258 )
产品货号. M17618 CAS No. 852433-84-2
Dovitinib Dilactic acid (TKI258 Dilactic acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor.
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥608 | 有现货 |
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10MG | ¥923 | 有现货 |
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25MG | ¥1895 | 有现货 |
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50MG | ¥3281 | 有现货 |
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100MG | ¥5249 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Dovitinib Dilactic Acid
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Dovitinib Dilactic acid (TKI258 Dilactic acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor.
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产品描述Dovitinib Dilactic acid (TKI258 Dilactic acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4.
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同义词Dovitinib Dilactic acid; TKI258 Dilactic acid; CHIR-258, TKI258
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通路Metabolic Enzyme/Protease
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靶点Dehydrogenase
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受体c-Kit; FGFR1; FGFR3; FLT3; VEGFR3/FLT4
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研究领域Cancer
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适应症——
化学信息
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CAS Number852433-84-2
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分子量572.59
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分子式C21H21FN6O·2C3H6O3
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纯度98%
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溶解度——
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SMILESCC(C(=O)O)O.CC(C(=O)O)O.CN1CCN(CC1)C2=CC3=C(C=C2)N/C(=C/4\C(=C5C(=NC4=O)C=CC=C5F)N)/N3
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化学全称2-Hydroxypropanoic acid compd. with 4-amino-5-fluoro-3-[6-(4-methyl-1- piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Trudel S, et al. Blood. 2005, 105(7), 2941-2948.
产品手册
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